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# Monoclonal antibody therapy and other biological modalities - Whole blood and components

## Essential information

Includes

  Systemic treatment with monoclonal antibody (MAb) treatments

Obligatory

  See: is there is a specific entry for the treatment and/or condition you are concerned about?

  Must not donate.

Discretionary
  1. If an individual monoclonal antibody treatment is listed in the entry for the underlying condition, apply guidance as per that entry.
  2. If the underlying condition does not preclude donation, and it is more than 6 months from last treatment, accept.

## Supporting information

See if relevant
  - Asthma
  - Autoimmune disease
  - Clinical trials
  - Dermatitis
  - Eye disease
  - Hypercholesterolaemia
  - Migraine
  - Osteopenia
  - Psoriasis
Additional information

  The use of monoclonal antibody and other biological therapies continues to expand. Care should be taken to understand the type of treatment and the indication, which may not be included in the See if relevant section above.

  Current scientific literature does not provide conclusive evidence to reject concerns that individuals on these treatments are more prone to infection. Until further clarity is provided in the literature, donors on these medications are withdrawn, unless otherwise stated.

Reason for change:
  Links to conditions that are currently commonly treated with monoclonal antibody therapies have been added to the ‘See if Relevant’ section, with reference to the expansion in types of treatment and use of these treatments within the ‘Additional Information’ section.
Version details:

  WB-DSG Edition 203 Release 74 (26 November 2024)

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